PARKINSON DISEASE

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PARKINSON DISEASE

The Parkinson's Disease is a progressive neurological disorder with nerve cell loss in a small area called Substantia Nigra, located on the brain stem. Although the cause of this disease is unknown in many patients, Parkinson-like conditions are usually seen after head trauma, stroke, encephalitis or some drug poisoning. The onset age of the disease is usually 50-60 years. The main symptoms of Parkinson's disease include stiffness, slowness of motion, walking related problems, and trembling. Patients experience "off" periods that their complaints increase and "on" periods that their motions normalize. Initially, complaints respond well to medicines, but during the following years, off periods become more frequent and undesirable dyskinesias occur in next periods. Finally, providing a condition that keeps patients away from the off-period by drugs alone is difficult and the duration of treatment is prolonged.